Figure 4. Activity (P30): Analysis of activity over 4 repeated measurements showed an overall increase in A) locomotion [F(1,71) = 7.12, p = 9×10−3] and B) distance [F(1,71) = 7.36, p = 8.37×10−3], but no change on C) speed [F(1,74) = 1.92, p = 1.69] in propofol treated animals.
Propofol treatment did not alter D) anxiety related behavior in adolescent animals [F(1,74) = 0.02, p = 0.89]. An overall change in activity was observed over individual measurements, resulting in a significant decrease in locomotion [F(3,71) = 13.6, p = 4.08×10−7] and distance [F(3,71) = 5.35, p = 2.23×10−3] and a significant increase in speed [F(3,74) = 15.7, p = 5.53×10−8] and the index of anxiety [F(3,74) = 7.25, p = 3×10−4]. (ncontrols = 12 animals, npropofol = 8 animals).