Figure 2. IP-10 production by OCT4-specific T cells. (A and B) MACS-sorted CD4⁺ and CD8⁺ cells were stimulated with autologous dendritic cells (DCs) loaded as indicated, and after 2 d of co-culture interferon γ (IFNγ)-inducible protein 10 (IP-10) secretion was assessed by ELISA. (A) IP-10 production by T cells exposed to autologous DCs loaded with an immunoreactive OCT4-derived peptide (representative data from one donor). (B) IP-10 production by T cells exposed to autologous DCs loaded with the OCT4 mRNA (representative data from the same donor).