Table 4. HAI antibody responses to immunization with 2010 TIV vaccine, in adults previously given adjuvanted H1N1 2009 pandemic vaccine.
| Parameter | A/H1N1/2009 | A/H3N2 (Perth) | B (Brisbane) |
|---|---|---|---|
|
A. Baseline (n = 325) |
|
|
|
| HAI ≥ 10 |
303 (93.2%) |
167 (51.4%) |
323 (99.4%) |
| HAI ≥ 40 |
176 (54.2%) |
60 (18.5%) |
272 (83.7%) |
| (95% CI) |
(48.6, 59.7) |
(14.4, 23.1) |
(79.2, 87.5) |
| GMT |
37.4 |
13.1 |
99.4 |
| (95% CI) |
(32.8, 42.6) |
(11.9, 14.4) |
(88.0, 112) |
|
B. Post-immunization (n = 321) |
|
|
|
| HAI ≥ 40 |
308 (96.0%) |
230 (71.7%) |
317 (98.8%) |
| (95% CI) |
(93.2, 97.8) |
(66.4, 76.5) |
(96.8, 99.7) |
| GMT |
167.4 |
61.3 |
225.5 |
| (95% CI) |
(148.7, 188.5) |
(53.2, 70.6) |
200.2, 254.1) |
| GM fold rise |
4.4 |
4.7 |
2.28 |
| (95% CI) |
(3.9, 5.0) |
(4.1, 5.3) |
(2.0, 2.6) |
| Seroconversion |
191 (59.5%) |
180 (56.1%) |
86 (26.5%) |
| (95% CI) | (53.9, 64.9) | (50.5, 61.6) | (21.7, 31.6) |