Figure 6. Cytotoxicity of effector CTLs against target HMEC plotted according to equation (Eq) that describes the dependence of cytotoxicity from the correlation of cell surface profiles (r) and intensity of tumor-induced changes (k) at the HMEC surface. Autologous EC antigens were used to induce CTLs. Correlation values (coefficient r) were calculated for HMEC surface profiles used to generate antigens (EAA) for eliciting immune response and the surface profile of target HMEC used in same cytotoxicity assay. Results of cytotoxicity assays are projected on the plot. “1►2” -1st letter corresponds to HMEC used to generate antigens (EAA) for eliciting immune response in the cytotoxicity assays; 2nd letter corresponds to the target HMEC used in the same cytotoxicity assay. “G” -¹HMEC_ECGS; “M” -¹HMEC_MCF-7; “L”- ¹HMEC_LNCap; “H” -¹HMEC_HepG2. The equation was developed from equations described in the “Discussion.”