Table 1.

Baseline characteristics (raw number and percentage) for those with and without a lower extremity amputation (LEA).

	White N=1550		African-American N=1490
	No LEA	LEA	No LEA	LEA
Subcohort N(%)	1481 (95.6)	69 (4.4)	1397 (93.8)	93 (6.2)
Women N(%)	603 (96.0)	25 (4.0)	731 (95.9)	31 (4.1)^
Age by category N (%)
<40	106 (98.2)	2 (1.8)	97 (94.1)	6 (5.8)
>=40 - <50	169 (98.8)	2 (1.2)	170 (95.0)	9 (5.0)
>=50 - <60	376 (93.3)	27 (6.7)	424 (92.6)	34 (7.4)
>=60 - <70	578 (95.8)	25 (4.2)	516 (93.6)	35 (6.4)
>=70	252 (95.1)	13 (4.9)*	190 (95.5)	9 (4.5)
Diabetes N (%)	569 (90.8)	58 (9.2)^	690(89.4)	82 (10.6)^
eGFR ml/min/1.73m2
mean (sd)	44.0 (12.8)	39.2 (10.4)#	43.9 (13.9)	39.5 (13.9)#
eGFR > 60 N(%)	150 (98.7)	2 (1.3)	177 (95.7)	8 (4.3)
eGFR 30 – 60	1086 (95.4)	52 (4.6)	977 (94.4)	58 (5.6)
eGFR < 30	245 (94.2)	15 (5.8)*	243 (90.0)	27 (10.0)
ABI mean (sd)	1.11 (0.2)	1.11 (0.4)	1.06 (0.2)	0.99 (0.2)*
ABI <0.90 N(%)	139 (90.8)	14 (9.2)^	210(90.51)	22 (9.4)*
Diagnosis of PVD N(%)	71 (71.0)	29 (29.0)^	83 (75.5)	27 (24.5)^
BMI mean (sd)	31.1 (7.4)	34.0 (8.2)#	33.4 (8.3)	34.0 (8.1)

Significant testing for comparisons between those with and without LEA. Categorical variables assessed with respect to trend. p-values

^*<0.05

^#≤ 0.002

^{^}≤ 0.0002