Table 1.
Tissue | Subset | Cell number (× 10−5) |
|||
---|---|---|---|---|---|
Wild-type PBS | CD19−/− PBS | Wild-type OVA | CD19−/− OVA | ||
Spleen | B220+ | 499 ± 45 | 235 ± 32∗∗ | 532 ± 58 | 262 ± 39∗∗ |
CD1d hiCD5+B220+ | 16 ± 3 | 0.2 ± 0.1∗∗ | 20 ± 4 | 0.3 ± 0.1∗∗ | |
CD4+CD25+FoxP3+ | 15 ± 2 | 14 ± 3 | 21 ± 3∗ | 20 ± 4∗ | |
Draining lymph node | B220+ | 11 ± 2 | 12 ± 3 | 14 ± 3 | 14 ± 2 |
CD4+CD25+FoxP3+ | 2.5 ± 0.4 | 2.3 ± 0.6 | 4.4 ± 0.8∗∗ | 4.9 ± 1.0∗∗ | |
Peritoneal cavity | B220+ | 12 ± 1.8 | 2.5 ± 0.4∗∗ | 11 ± 2.2 | 2.3 ± 0.1∗∗ |
CD5+B220+ | 1.5 ± 0.4 | 0.09 ± 0.02∗∗ | 1.6 ± 0.3 | 0.08 ± 0.03∗∗ |
Data are expressed as means ± SEM of at least four mice.
∗P < 0.05, ∗∗P < 0.01 versus PBS-sensitized wild-type mice.