Table 2.
Incidence of HGUPS, LMS, and CS per Genotype
| Genotype |
Incidence∗ | Tumor distribution∗ |
||||
|---|---|---|---|---|---|---|
| Tagln-cre | Pten | Tp53 | HGUPS | LMS | CS | |
| + | +/+ | +/+ | 0/28 | 0/0 | 0/0 | 0/0 |
| + | Δ/+ | Δ/+ | 14/37 (38) | 9/14 (64.3) | 3/14 (21.4) | 2/14 (14.3) |
| + | Δ/+ | +/+ | 4/40 (10) | 2/4 (50) | 1/4 (25) | 1/4 (25) |
| + | +/+ | Δ/+ | 6/27 (22.2) | 2/6 (33.3) | 3/6 (50) | 1/6 (22.2) |
+, wild-type allele; Δ, floxed allele; CS, carcinosarcomas; HGUPS, high-grade undifferentiated pleomorphic sarcomas; LMS, leiomyosarcomas.
∗
Data are given as number/total (percentage).