Table 2.
Genomic Regions with CNN-LOH/UPD in Major SGCs
| Chromosome | Cytoband | Position | ACC (%) | MEC (%) | SDC (%) |
|---|---|---|---|---|---|
| 1 | p36.33–p36.22 | 775852–9341877 | 16 | 0 | 0 |
| 1 | q43–q43 | 236829721–240601698 | 0 | 10 | 5 |
| 2 | q11.2–q12.2 | 100704414–105985632 | 0 | 5 | 10 |
| 2 | q14.2–q14.3 | 119250745–124670233 | 5 | 5 | 5 |
| 3 | p24.3–p24.2 | 21618434–25295115 | 0 | 5 | 10 |
| 3 | p12.3–q11.2 | 78686977–96257804 | 0 | 0 | 15 |
| 5 | q33.2–q35.3 | 153512108–180629495 | 0 | 5 | 10 |
| 6 | q21–q22.1 | 109415645–114741718 | 0 | 0 | 15 |
| 9 | p24.3–p24.1 | 140524–6300829 | 0 | 10 | 5 |
| 9 | p22.3–p22.1 | 15942197–18968625 | 11 | 5 | 0 |
| 9 | p21.2–p21.1 | 27800651–31371316 | 11 | 0 | 0 |
| 9 | p21.1–p13.2 | 31373712–37537256 | 5 | 10 | 0 |
| 9 | p13.2–q21.13 | 37574687–73460374 | 0 | 15 | 0 |
| 9 | q22.33–q31.1 | 99537571–104645839 | 0 | 10 | 5 |
| 9 | q33.1–q33.1 | 117901921–121619119 | 5 | 5 | 5 |
| 9 | q33.3–q34.3 | 128519158–140147760 | 5 | 5 | 5 |
| 10 | q21.1–q21.1 | 57418162–61122758 | 5 | 5 | 10 |
| 10 | q21.1–q21.3 | 61177020–66136170 | 0 | 5 | 10 |
| 11 | p15.1–p14.3 | 20031569–23207906 | 5 | 0 | 10 |
| 11 | p13–p13 | 31282908–35998329 | 5 | 0 | 10 |
| 11 | p11.2–q11 | 44781630–56339353 | 0 | 0 | 10 |
| 11 | q12.3–q13.4 | 62942205–74605123 | 0 | 5 | 10 |
| 11 | q14.1–q14.3 | 84276650–88310071 | 0 | 5 | 10 |
| 12 | q14.1–q14.3 | 58492903–64094393 | 0 | 0 | 15 |
| 12 | q14.3–q15 | 64124796–68546087 | 0 | 0 | 10 |
| 12 | q15–q21.1 | 68546631–73477497 | 0 | 0 | 15 |
| 12 | q21.2–q21.31 | 78005428–83047419 | 0 | 0 | 10 |
| 12 | q21.31–q21.33 | 83065065–88560841 | 0 | 5 | 10 |
| 14 | q12–q21.1 | 29399863–39750495 | 5 | 0 | 10 |
| 18 | q12.2–q12.3 | 34364676–39279784 | 0 | 5 | 10 |
Data show the number of CNN-LOH events that occurred in ACCs, MECs, and SDCs. The table lists only those genomic regions that had at least three events. The events were identified using allele-specific CNAs that were significantly different from the reference level, whereas the total CNA was not significantly different in a scanning window (for details, see Materials and Methods).
UPD, uniparental disomy.