Table 3.
Amplicons at Different Chromosomal Regions in Major SGCs
| Sample | Cytoband | Position∗ | CNA | Gene |
|---|---|---|---|---|
| ACC1 | 11q23.3–24.1 | 118706909–122013373 | 9.9 | PVRL1 |
| MEC1 | 11q13.3–q13.4 | 70322842–71448250 | 7.2 | NUMA1 |
| SDC1 | 17q12 | 35084426–35264341 | 10.8 | ERBB2 |
| SDC10 | 12q15 | 68689573–69077882 | 7.0 | CNOT2, RAB3IP |
| SDC10 | 9p13.2 | 36791146–36905407 | 7.1 | PAX5 |
| SDC18† | 17q12 | 31473221–31501499 | 6.9 | CCL4 |
| SDC19 | 17q12 | 35130293–35264341 | 6.6 | ERBB2 |
| SDC2 | 17q12 | 34786442–35130293 | 12.0 | ERBB2 |
| SDC4 | 6p21.1 | 41772099–42368678 | 6.0 | CCND3 |
| SDC7 | 12q21.1–q21.2 | 73790896–74456589 | 6.9 | GLIPR1L1 |
A segment was defined as an amplicon if the mean copy number was higher than six.
The genomic intervals of the segments are shown.
The amplicon at 17q12 in sample SDC18 encodes no known gene. The nearest gene, CCL4, is shown instead.