Table 2.
Whole Blood Platelet Aggregation
| Variable | Whole blood |
|||||
|---|---|---|---|---|---|---|
| ADP (10 μmol/L; n = 8) |
Col (3 μg/mL; n = 8) |
AA (0.5 mmol/L; n = 12) |
||||
| WT | Fut−/− | WT | Fut−/− | WT | Fut−/− | |
| LT (seconds) | 27.0 ± 0.6 | 22.2 ± 0.5∗ | 88.1 ± 3.2 | 78.0 ± 2.1∗ | 39.8 ± 6.2 | 20.8 ± 1.3∗ |
| Slope | 16.4 ± 1.0 | 21.4 ± 0.9∗ | 12.0 ± 0.8 | 14.8 ± 0.7∗ | 9.1 ± 2.2 | 19.3 ± 0.8∗ |
| MA (%) | 12.1 ± 0.6 | 13.0 ± 0.7 | 14.1 ± 0.6 | 13.5 ± 0.6 | 3.0 ± 0.9 | 9.8 ± 0.7∗ |
All values represent means ± SD.
AA, arachidonic acid; Col, collagen; LT, lag time; MA, maximum amplitude.
P < 0.05 vs the corresponding WT.