Table 2.
Variable | Duration of atherogenic diet |
|||
---|---|---|---|---|
6 Weeks |
12 Weeks |
|||
Col8+/+;ApoE−/− | Col8−/−;ApoE−/− | Col8+/+;ApoE−/− | Col8−/−;ApoE−/− | |
Mean arterial pressure (mmHg) | 66.3 ± 3.6 (n = 8) | 61.3 ± 2.1 (n = 8) | 70.4 ± 2.8 (n = 8) | 66.4 ± 2.1 (n = 8) |
Heart rate (beats/minute) | 491 ± 19 (n = 8) | 455 ± 14 (n = 8) | 523 ± 28 (n = 8) | 487 ± 14 (n = 8) |
Body weight (g) | 25.4 ± 1.1 (n = 15) | 27.0 ± 0.9 (n = 18) | 30.0 ± 1.1 (n = 13) | 31.8 ± 1.3 (n = 17) |
Plasma triglyceride concentration (mmol/L) | 1.45 ± 0.16 (n = 9) | 1.65 ± 0.19 (n = 12) | 1.64 ± 0.09 (n = 10) | 1.78 ± 0.16 (n = 13) |
Plasma cholesterol concentration (mmol/L) | 16.8 ± 1.2 (n = 9) | 22.1 ± 1.3∗ (n = 12) | 16.3 ± 1.0 (n = 10) | 19.0 ± 1.2 (n = 13) |
Values represent means ± SEM. Sample size is indicated in parentheses.
P ≤ 0.05