Figure 2.

Sample model fits to ¹⁸O-CO₂ data for the determination of eCA activity. Cells expressing eCA were added to the assay solution at time 0, accelerating ¹⁸O removal. A shows a good fit to the data. B shows an example where a better fit can be achieved by reducing f_b-BL 10-fold, but the eCA activities are similar in both fits (base, k_sf = 1.7 × 10⁻⁶; reduced, f_b-BL k_sf = 1.5 × 10⁻⁶). For clarity, only every other ¹⁸O-CO₂ data point is shown.