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Categories of WGD-duplicated genes based on the divergence of protein interaction partners. Blue circles represent WGD-duplicated paralogous gene pairs. Orange squares are the original interacting partners shared by both copies. Red triangles are newly gained interacting partners indicating function divergence. Arrows suggest the process of function divergence of WGD-duplicated genes. The top and bottom paths refer to divergence by loss and gain of interaction partners, respectively.
