Table 2.
Demographics With Regard to FAD Mutation Status
| Characteristic | No. (%)
|
P Value | |
|---|---|---|---|
| FAD Mutation Carriers (n = 21) | FAD Mutation Noncarriers (n = 12) | ||
| Age, median (range), y | 32.8 (19–55) | 38.8 (19–59) | .11 |
| Adjusted age, mean (SD), ya | −12.4 (11.0) | −6.8 (15.9) | .25 |
| Female sex | 16 (76) | 9 (75) | .99 |
| APOE allele | |||
| 2/3 | 5 (24) | 1 (8) | .38 |
| 3/3 | 14 (67) | 7 (58) | .72 |
| 3/4 | 2 (10) | 4 (33) | .16 |
Abbreviation: FAD, familial Alzheimer disease.
a
Adjusted age is the participants’ ages in relationship to the median age of dementia diagnosis in the family.