Table 5.
Patients’ characteristics and causes of death of 21 patients who died in trial of double or standard dose oseltamivir for treatment of severe influenza
| Country | Virus | Sex | Age | Day of illness on admission | Day since admission at death | Cause of death |
|---|---|---|---|---|---|---|
| Double dose arm | ||||||
| Indonesia | ND | F | 18 | 9 | 2 | Respiratory failure |
| Vietnam | B | M | 43 | 6 | 7 | Respiratory failure |
| Vietnam | H3N2 | M | 2 | 5 | 13 | Respiratory failure |
| Vietnam | H3N2 | M | 54 | 7 | 1 | MOF |
| Vietnam | H5N1 | F | 28 | 7 | 12 | Severe hypoxaemia |
| Vietnam | H5N1 | M | 39 | 6 | 3 | Respiratory failure |
| Vietnam | H5N1 | M | 10 | 8 | 3 | Respiratory failure |
| Indonesia | H5N1 | F | 28 | 8 | 1 | ARDS and respiratory failure |
| Indonesia | H5N1 | F | 16 | 10 | 5 | ARDS |
| Indonesia | H5N1 | M | 30 | 7 | 4 | MOF |
| Indonesia | H5N1 | F | 31 | 8 | 5 | MOF |
| Vietnam | H5N1 | M | 3 | 5 | 2 | ARDS and shock |
| Standard dose arm | ||||||
| Vietnam | ND | M | 44 | 6 | 1 | MOF |
| Vietnam | H1N1pdm09 | F | 22 | 6 | 4 | MOF |
| Vietnam | H5N1 | M | 31 | 5 | 1 | Respiratory failure |
| Indonesia | H5N1 | M | 8 | 3 | 1 | Respiratory failure |
| Indonesia | H5N1 | M | 9 | 10 | 1 | Respiratory failure |
| Indonesia | H5N1 | F | 30 | 6 | 2 | ARDS and respiratory failure |
| Indonesia | H5N1 | M | 47 | 7 | 2 | Septic shock |
| Indonesia | H5N1 | M | 32 | 10 | 2 | MOF |
| Indonesia | H5N1 | F | 29 | 10 | 1 | Respiratory failure |
ND=no influenza virus detected; ARDS=acute respiratory distress syndrome, MOF=multi-organ failure.