Table 3.
Additional significant SNPs or positive results identified by eQTL weighting methods after accounting for linkage disequilibrium in the GABRIEL analysis.
| Chr | SNP | Gene | p-value | Qg | Qb | Method |
|---|---|---|---|---|---|---|
| 5 | rs736801 | 2.15 × 10−7 | 8.81 × 10−8 | 5.29 × 10−8 | Bonferroni, Holm | |
| 6 | rs2596450 | HCG26 | 2.72 × 10−7 | 1.16 × 10−7 | 6.69 × 10−8 | Bonferroni, Holm |
| 5 | rs10075941 | 6.13 × 10−5 | 3.03 × 10−5 | 1.51 × 10−5 | BH | |
| 17 | rs17637472 | 6.13 × 10−5 | 3.56 × 10−5 | 1.51 × 10−5 | BH | |
| 5 | rs244749 | MEF2C | 6.25 × 10−5 | 2.51 × 10−5 | 1.54 × 10−5 | BH |
| 9 | rs7047575 | 6.87 × 10−5 | 3.92 × 10−5 | 1.69 × 10−5 | BH | |
| 17 | rs7503195 | 7.66 × 10−5 | 3.07 × 10−5 | 1.88 × 10−5 | BH | |
| 6 | rs9273363 | HLA_DQB1 | 8.38 × 10−5 | 4.41 × 10−5 | 2.06 × 10−5 | BH |
| 5 | rs4351182 | 9.98 × 10−5 | 4.91 × 10−5 | 2.45 × 10−5 | BH | |
| 2 | rs13391794 | 1.01 × 10−4 | 5.62 × 10−5 | 2.49 × 10−5 | BH | |
| 5 | rs10044342 | MEF2C | 1.10 × 10−4 | 4.59 × 10−5 | 2.71 × 10−5 | BH |
| 2 | rs6751196 | 1.14 × 10−4 | 6.22 × 10−5 | 2.80 × 10−5 | BH | |
| 6 | rs176095 | PBX2, GPSM3 | 1.25 × 10−4 | 5.12 × 10−5 | 3.08 × 10−5 | BH |
| 2 | rs2675073 | 1.34 × 10−4 | 5.40 × 10−5 | 3.29 × 10−5 | BH | |
| 2 | rs1913621 | 1.46 × 10−4 | 7.92 × 10−5 | 3.60 × 10−5 | BH | |
| 2 | rs10497621 | NUP35 | 1.59 × 10−4 | 7.55 × 10−5 | 3.91 × 10−5 | BH |
| 5 | rs244750 | MEF2C | 1.70 × 10−4 | 7.08 × 10−5 | 4.17 × 10−5 | BH |
| 6 | rs9366689 | POM121L2 | 1.72 × 10−4 | 8.73 × 10−5 | 4.23 × 10−5 | BH |
| 6 | rs7775759 | 1.81 × 10−4 | 6.43 × 10−5 | 4.46 × 10−5 | BH | |
| 6 | rs7741091 | 1.81 × 10−4 | 6.43 × 10−5 | 4.46 × 10−5 | BH | |
| 8 | rs6601649 | 1.90 × 10−4 | 9.68 × 10−5 | 4.68 × 10−5 | BH | |
| 6 | rs204994 | 1.94 × 10−4 | 8.02 × 10−5 | 4.76 × 10−5 | BH |
The results are based on the binary weight.