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The molecular signature for IFN signaling is specific to the adult definitive erythroid lineage. In the microarray expression dataset, genes involved upstream (A) or downstream (B) of IFN-signaling were found to be preferentially expressed during adult definitive erythropoiesis. This includes Ifng and downstream apoptotic (Casp1, Tnfsf10) and anti-apoptotic genes (e.g., Bcl2l, Bcl2).
