Table 1.

Use and costs of healthcare for pneumococcal disease by disease outcome per case [48]

	Healthcare costs
Disease outcome	Mean direct costs per casea	Mean indirect costs per casea
Meningitis	€ 15,255.00	€ 302.00
Pneumonia requiring GP consultation	€ 17.10	€ 6.50
Pneumonia requiring hospitalization	€ 5,194.00	€ 173.00
Bacteraemia	€ 8,077.00	€ 197.00

^a The main direct and indirect costs were calculated by taking the age-related resource information published in Jansen et al. [19] and the direct medical costs and indirect costs of productivity losses registered by the Statistics Netherlands (//statline.cbs.nl, in Dutch).