Table 2.
Substrate |
α-glucosidases inhibitory activities, IC50 (mg/ml) |
||||||
---|---|---|---|---|---|---|---|
SF (var. angustifolia) |
BF (var. kunstleri) |
Acarbose | |||||
SFC | SFE | SFW | BFC | BFE | BFW | ||
Yeast α-glucosidase |
|
|
|
|
|
|
|
pNPG |
0.065 ± 0.005a |
0.259 ± 0.014b |
0.083 ± 0.006a |
0.061 ± 0.003c |
0.225 ± 0.008d |
0.049 ± 0.003e |
9.075 ± 0.065 |
Rat intestinal α-glucosidase |
|
|
|
|
|
|
|
Sucrose |
0.552 ± 0.013a |
0.611 ± 0.020a |
0.473 ± 0.011b |
0.538 ± 0.016c |
0.596 ± 0.015c |
0.444 ± 0.004d |
0.039 ± 0.001 |
pNPG | 7.226 ± 0.389a | 13.957 ± 0.238b | 7.173 ± 0.170a | 6.407 ± 0.102c | 10.040 ± 0.291d | 4.123 ± 0.136e | 0.058 ± 0.001 |
Each value is expressed as a mean ± SD of triplicates from three different experiments. Values with different superscript letters between the same variety, within the same row are significantly different at p < 0.01. SFC, SFE and SFW indicate crude aqueous extract, ethyl acetate fraction and water fraction of SF (var. angustifolia). BFC, BFE and BFW indicate crude aqueous extract, ethyl acetate fraction and water fraction of BF (var. kuntsleri).