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. Author manuscript; available in PMC: 2014 Jun 1.
Published in final edited form as: Hematol Oncol Clin North Am. 2013 Apr 13;27(3):541–563. doi: 10.1016/j.hoc.2013.02.001

Table 3. Immunoassays available for the detection of PF4/H Abs.

Assay Vendor Polyclonal v.
IgG Specific
Principle Sensitivity Specificity
Asserachrom IgGAM Diagnostica Stago Polyclonal ELISA 100%71,89 64%-86.46%71,89
GTI PF4 IgG GTI Diagnostics IgG specific ELISA 100%89,123 42%-95.92%89,123
HemosIL AcuStar HIT-
Ab(PF4-H)
Instrumentation
laboratory
Polyclonal Latex
enhanced
immunoturbidi
metric assay
100%124 81.2%124
HemosIL AcuStar HIT-
IgG(PF4-H)
Instrumentation
laboratory
IgG specific Latex
enhanced
immunoturbidi
metric assay
100%124 96.5%124
ID-heparin/PF4
PaGIA
Diamed Polyclonal particle gel
immunoassay
94%-100%71,72,125 61%-95%71,72,125
Poly-ELISA GTI Diagnostics Polyclonal ELISA 100%72 80.8%72
Zymutest HIA IgG Hyphen Biomed
Research
IgG specific ELISA 100%89,123 44%-95.92%89,123
Zymutest HIA IgGAM Hyphen Biomed
Research
Polyclonal ELISA 100%89 87.50%89

Enzyme linked immunoassay, ELISA