Skip to main content
. Author manuscript; available in PMC: 2013 May 31.
Published in final edited form as: J Biol Chem. 2006 Mar 29;281(22):15258–15267. doi: 10.1074/jbc.M512953200

FIGURE 5. jnk2−/− mice have increased long-term survival after GalN/LPS treatment.

FIGURE 5

A, percentages of survival of wild-type (WT), jnk1−/−, and jnk2−/− mice at the indicated hours after administration of GalN/LPS. Data are from 3 independent experiments that include a total of 19 wild-type, 10 jnk1−/−, and 25 jnk2−/− mice (p < 0.01 for jnk2−/− as compared with wild type or jnk1−/−). B, serum ALT levels in wild-type mice surviving for the indicated hours after GalN/LPS treatment. C, graded histological scoring of the degree of apoptosis (Apop) and inflammation (Inflam) in the livers of the same animals. D, numbers of TUNEL-positive cells per high power field in the identical liver sections. Data in B–D are from four independent experiments and total three-eight animals per data point.

HHS Vulnerability Disclosure