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. 2012 Apr 10;67(11):1153–1160. doi: 10.1093/gerona/gls103

Figure 3.

Figure 3.

Prevalence of homozygosity (CC) for the MTP rs2866164 SNP according to age and adjustment for buffering genotypes in Ashkenazi Jews. (A) Frequency of MTP CC genotype in controls and probands (range 55–104 years) by the specified age ranges with the indicated number of subjects for each age range: 55–64 years = 44, 65–74 years = 101, 75–84 years = 97, 85–94 years = 60, and 95–104 years = 179. (B) The frequency of homozygosity for the CC genotype of the MTP rs2866164 SNP according to age with or without buffering genes in offspring and controls (see Methods for description of CETP [rs5882], ApoC3 [rs2542052], AdipoQ [rs56354395]). Filled circles (and continuous line) indicate prevalence of the CC homozygosity in those that did not harbor buffering genes. Open circles (and dashed line) indicate prevalence of the CC homozygosity in participants that harbor buffering genes. Frequency of MTP CC genotype either with or without buffering genes are given by the specified age ranges with the indicated number of subjects for each age range (buffered/unbuffered): 55–64 years = 32/51, 65–74 years = 50/72, 75–84 years = 42/58, 85–92 years = 9/22.