Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2013 Mar 28;108(8):1720–1731. doi: 10.1038/bjc.2013.132

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2013 Cancer Research UK

From twelve months after its original publication, this work is licensed under the Creative Commons Attribution-NonCommercial-Share Alike 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/3.0/

PMC Copyright notice

Colosphere chemosensitivity responses reflect in vivo parent colon PDX responses. (A) Effect of 5-FU on CR-IGR-007P (low responder) and CR-LRB-004P (high responder) colon cancer xenografts (in vivo) and paired colospheres viability and cytotoxicity (ex vivo graphs). (B) Effect of irinotecan on CR-IC-004M (low responder) and CR-LRB-018P (high responder) colon cancer xenografts (in vivo) and paired colospheres viability and cytotoxicity (ex vivo graphs). Data points are means±s.e.m. with 8–10 animals per group for in vivo experiments and with six-wells treated and measured per condition for ex vivo experiments. The results shown in ex vivo graphs are from one experiment taken as representative of, at least, three independent experiments.