Table 4. Expression levels of 15 genes downregulated by miR-874 in ‘cell cycle' pathway (GSE9844).
| Entrez gene | Symbol | Fold change (tumour/normal) | P-value |
|---|---|---|---|
| 898 |
CCNE1 |
2.262 |
0.0012 |
| 3065 |
HDAC1 |
1.539 |
0.0012 |
| 994 |
CDC25B |
1.782 |
0.0023 |
| 8697 |
CDC23 |
1.331 |
0.0095 |
| 1021 |
CDK6 |
1.932 |
0.0118 |
| 1027 |
CDKN1B |
−1.569 |
0.0644 |
| 5885 |
RAD21 |
1.567 |
0.0897 |
| 5934 |
RBL2 |
−1.622 |
0.0945 |
| 2932 |
GSK3B |
1.276 |
0.1100 |
| 7042 |
TGFB2 |
1.405 |
0.1158 |
| 9184 |
BUB3 |
1.162 |
0.1239 |
| 51 529 |
ANAPC11 |
1.264 |
0.2215 |
| 5925 |
RB1 |
1.076 |
0.7581 |
| 4088 |
SMAD3 |
−1.076 |
0.8110 |
| 1032 | CDKN2D | 1.089 | 0.9277 |
Abbreviation: miR-874=microRNA-874.