Table 2. Distribution of clinical disease response (absolute and percentage value) at individual end according to single cohort.
Cohort A | Cohort B | Cohort C | |
---|---|---|---|
No. of patients |
40 |
40 |
40 |
NA |
0 |
2 |
0 |
Progressive disease |
4 (10.0) |
1 (2.6) |
0 |
Stable disease |
18 (45.0) |
4 (10.5) |
2 (5.0%) |
Partial response |
13 (32.5) |
17 (44.8) |
15 (37.5%) |
Complete response |
5 (12.5) |
16 (42.1) |
23 (57.5) |
Overall response rate |
45.0% |
86.8% |
95.0% |
95% CI | 29.3–61.5 | 71.9–95.6 | 83.1–99.4 |
Abbreviations: CI=confidence interval; NA=not available.