Table 1.
Chemical properties of naloxone, naltrexone, hydromorphone and butorhpanol [36]
| Drug Name | Molecular Weight | pKa | Log P |
|---|---|---|---|
| Naloxone | 327 | 7.9 | 2 |
| Naltrexone | 341 | 8.1 | 1.9 |
| Hydromorphone | 285 | 8.5 | 1.8 |
| Butorphanol Tartrate |
327 | 8.6 | 3.77 |
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