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. 2013 Apr 8;288(22):15442–15454. doi: 10.1074/jbc.M112.447185

FIGURE 3.

FIGURE 3.

Overview and structural footprints of the SB27, CA5, and SB47 TCRs. Overview (upper panels) of the SB27 (A), CA5 (B), and SB47 (C) TCRs bound to HLA-B*35:08 (white) presenting the LPEP peptide (black). The color scheme is consistent across all panels and the orientation of HLA-B*35:08 is identical. TCR α- and β-chain framework residues are colored in pale pink and cyan, respectively. CDR1α, purple; CDR2α, green; CDR3α, red; CDR1β, yellow; CDR2β, sand; CDR3β, orange. The structural footprints (lower panels) of the SB27 (A), CA5 (B), and SB47 (C) TCRs onto HLA-B*35:08LPEP are shown as surface representation with atoms colored based on the corresponding CDR loops that mediate the contacts. The black spheres represent the center of mass for the Vα and Vβ domains.