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Dissociation constants for p51 connection subdomain mutants p66/p51F416A to p66/p51P421A
Values represent the average of triplicate experiments and were determined on an RNA/DNA hybrid.
| p51 mutation | KD |
|---|---|
| nm | |
| WT | 66.1 ± 10.5 |
| F416A | 218.3 ± 35.3 |
| V417A | 65.0 ± 15.2 |
| F416A | 40.4 ± 8.3 |
| N419A | 131.2 ± 13.9 |
| P420A | 92.4 ± 12.0 |
| P421A | 114.8 ± 10.8 |
