Table 1.

Selected baseline characteristics by treatment assignment.

Characteristic	Intervention arm (N =1371), n/N (%)	Control arm (N =1378), n/N (%)
HSV-2 seropositive	384/1370 (28.0)	343/1378 (24.9)
No GUD	356 (92.7)	312 (91.0)
GUD	28 (7.3)	31 (9.0)
HSV-2-seronegative	986/1370 (72.0)	1035/1378 (75.1)
No GUD	955 (96.9)	1017 (98.3)
GUD	31 (3.1)	18 (1.7)
Active syphilis	18/1368 (1.3)	9/1373 (0.7)
No GUD	16 (88.9)	8 (88.9)
GUD	2 (11.1)	1 (11.1)
Genital ulcer disease	59/1371 (4.3)	49/1378 (3.6)
HSV-2 seropositive and syphilis	1 (1.7)	1 (2.0)
HSV-2 seropositive only	27 (45.8)	30 (61.2)
Syphilis only	1 (1.7)	0 (0.0)
No causes	30 (50.8)	18 (36.7)

GUD, genital ulcer disease (detected by physical examination or by patient report); HSV-2, herpes simplex virus type 2.