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. Author manuscript; available in PMC: 2014 Jul 1.
Published in final edited form as: J Comput Phys. 2012 Aug 31;244:131–147. doi: 10.1016/j.jcp.2012.08.023

Figure 1.

Figure 1

Blood flow in the brain is a multiscale problem. Left: the macrodomain where the large-scale flow dynamics is modeled by the Navier-Stokes equations; different colors correspond to different computational patches (Courtesy of Prof. J.R. Madsen, Harvard Medical School). Shown in the inset are the microdomains where dissipative particle dynamics is applied to model the micro-scale features. Right: Scanning electron microscope image of the inside layer of a ruptured MCA aneurysm showing the disrupted pattern of endothelial cells and blood cells adhered to the inter-endothelial cell gaps [9].