Figure 6. .
Effects of elevated glucose and 670-nm PBM on RGC5 cells in vitro. Incubation in elevated glucose significantly increased expression of phosphorylated forms of AKT, p38 MAPK, and HSP 27, and downregulated expression of HO-1 (A–D). In each case, PBM (200 seconds, 25 mW/cm2, 5 J/cm2) significantly inhibited these abnormalities toward values seen in normal (5 mM) levels of glucose. The graphical data in the figures summarizes data from six dishes for each experimental condition.