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. 2013 May 1;123(6):2488–2501. doi: 10.1172/JCI67010

Figure 7. Correlation of ALDH1A2 protein expression and clinical outcome of OPSCC patients.

Figure 7

(A) Representative images at different power of ALDH1A2 expression on tissue microarrays of normal mucosa and exemplary tumors with low and high protein levels (brown signal). Counterstaining with hematoxylin. Scale bars: 100 μm. (B) Lower ALDH1A2 expression score in non–HPV-driven (n = 89) versus HPV-driven (n = 26) tumors. Bars denote medians. *P < 0.05, 2-tailed Mann-Whitney U test. Kaplan-Meier plots for OS (C) and PFS (D) with regard to ALDH1A2 protein levels in n = 115 OPSCC patients. P values were derived by log-rank/Mantel-Cox test.