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. 2013 May 8;123(6):2643–2653. doi: 10.1172/JCI66735

Figure 4. No detectable abnormalities in energy-related processes of constitutive and intestinal epithelium–specific Et2-null mice.

Figure 4

(A) Dietary fat absorption (left) and excretion of fats and carbohydrates (right) of 6-week-old “rescued” constitutive Et2-null and littermate WT mice (n = 5). (B) qRT-PCR analysis demonstrating intestine-specific deletion of Et2 by villin promoter–driven Cre recombinase (n = 5). Values are presented as fold change relative to ET-2 expression in stomach from control Et2f/f mice. (C) Body weight of Et2f/f;Vil-Cre and their littermate control Et2f/f mice (n = 21–23). (D) Blood glucose levels of Et2f/f;Vil-Cre and their littermate control Et2f/f mice at 2 weeks of age (n = 10). (E) Dietary fat absorption (left) and excretion of fats and carbohydrates (right) of 6-week-old Et2f/f;Vil-Cre mice and their littermate controls (n = 5). ND, not detected; NS, nonsignificant.