Figure 4.

Intranuclear Inclusions. (A) A pyramidal neuron and an astroglial cell in the frontal cortex containing intranuclear inclusion bodies. Note the pyramidal cell nucleolus adjacent to the intranuclear inclusion and the heterochromatin of the astroglial cell gathered up against the edges of the nucleus. (B) Granule neuron in the dentate gyrus of the hippocampus with an intranuclear inclusion body. (C) Granule neuron in the cerebellar granule cell layer with an intranuclear inclusion. Note the heterochromatin is pushed away from the inclusion, forming a dense gathering at the nuclear envelope. Scale bar = 50 μm applies to all plates.