Table 1.
Intranuclear inclusion counts
| |
Frontal Cortex |
Temporal Cortex |
Cerebellum |
Hippocampus--CA1 |
Hippocampus--DG |
|||||
|---|---|---|---|---|---|---|---|---|---|---|
|
(Gray Matter) |
(Gray Matter) |
(Granule Cell Layer) |
(Pyramidal Cell Layer) |
(Granule Cell Layer) |
||||||
| Neurons | Astroglia | Neurons | Astroglia | Neurons | Astroglia | Neurons | Astroglia | Neurons | Astroglia | |
| Case 1 |
7 of 206 |
19 of 421 |
4 of 189 |
25 of 311 |
30 of 1424 |
42 of 644 |
5 of 122 |
11 of 245 |
15 of 532 |
8 of 126 |
| mean |
3.40% |
4.51% |
2.12% |
8.03% |
2.10% |
6.52% |
4.09% |
4.49% |
2.82% |
6.35% |
| Greco et al., 2006 [8] |
4.4% |
16.7% |
na |
na |
na |
na |
10.1% |
10.3% |
2.1% |
26.6% |
| Tassone et al., 2012 [34] |
5.6% |
4.24% |
11.59% |
9.85% |
na |
na |
6.59% |
8.84% |
4.66% |
11.56% |
| Hunsaker et al., 2011 | 0.4% | 0.93% | na | na | na | na | na | na | 0.68% | 1.34% |
na Data not available.
This table shows the number of neurons and astroglia containing intranuclear inclusions in this Case as a function of the number of cells counted. Also included are intranuclear inclusion prevalence data from male FXTAS cases reported by [8], female FXTAS cases reported by [37], and male FXS reported by [26] to provide context for where along the fragile X associated disorder spectrum this size mosaic case fits.