Table 1.
Summary of patient demographic information by p16 status
| |
|
All patients (N= 406) |
p16 status available (N = 199) |
|||
|---|---|---|---|---|---|---|
| p16 + (N=118) | p16 - (N=81) | p-value | ||||
| Average age |
|
59.1 |
±10.9 |
55.9 |
60.7 |
0.003* |
| Sex |
Male |
327 |
79.8% |
86.6% |
76.3% |
0.047* |
| |
Female |
83 |
20.2% |
|
|
|
| Smokers |
|
281 |
68.5% |
63.5% |
86.8% |
0.0008* |
| Stage |
IV |
308 |
78.8% |
75.6% |
80.0% |
0.49 |
| |
III |
58 |
14.2% |
18.5% |
11.3% |
0.23 |
| |
II |
26 |
6.3% |
2.5% |
3.7% |
0.68 |
| |
I |
14 |
3.4% |
1.7% |
2.5% |
0.99 |
| Index tumour location |
Tonsils |
213 |
68.7% |
|
|
|
| |
Base of the tongue |
90 |
29.0% |
|
|
|
| |
Oropharynx NOS |
15 |
4.8% |
|
|
|
| |
Soft palate |
18 |
5.8% |
|
|
|
| |
Pharyngeal walls |
15 |
4.8% |
|
|
|
| Treatment |
Surgery+ChemoRT |
143 |
34.9% |
|
|
|
| |
ChemoRT |
216 |
52.7% |
|
|
|
| |
Palliative |
16 |
3.9% |
|
|
|
| |
Salvage surgery |
11 |
2.7% |
|
|
|
| |
No treatment |
21 |
5.1% |
|
|
|
| Follow-up (years) | 3.9 | ± 1.0 | 3.9 | 3.9 | 0.98 | |
p < 0.05 considered statistically significant. NOS = not otherwise specified.