The effect of LDH, VP16, and VP16-LDH of different VP16 concentrations on GES-1 cells and MKN45 and SGC-7901 tumor cells after 48 hours of incubation. (A) Cytotoxicity of LDH, VP16, and VP16-LDH of different VP16 concentrations to GES-1 cells after 48 hours. The effect of LDH, VP16, and VP16-LDH of different VP16 concentrations on the growth of MKN45 (B) and SGC-7901 (C) tumor cells after 48 hours.
Notes: Results represent the means of three independent experiments, and error bars represent the standard error of the mean. N = 3; *P < 0.05; **P < 0.001.
Abbreviations: LDH, layered double hydroxide; VP16, etoposide.