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. Author manuscript; available in PMC: 2013 Aug 2.
Published in final edited form as: Adv Mater. 2012 Jun 29;24(29):4014–4019. doi: 10.1002/adma.201201019

Figure 1. Synthesis of a library of ZnS-AgInS2QDs for simultaneous imaging and delivery of siRNA.

Figure 1

(A) Synthetic procedure to obtain a library of dodecylamine-capped hydrophobic ZAIS QDs. (B) Conversion of the the hydrophobic ZAIS QDs into water-soluble ones via ligand exchange with 3-mercaptopropionic acid (MPA) followed by attachment of siRNA using a layer-by-layer approach. (C) Delivery of the siRNA against EGFP using ZAIS QD-siRNA conjugates into brain cancer cells overexpressing EGFP.