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. 2013 Apr 12;21(1):31. doi: 10.1186/2008-2231-21-31

Table 1.

Cytotoxic activity (IC50, μg/ml) of compounds 5a-k against different cell lines in comparison with etoposide

Inline graphic
Compounds Ar MDA-MB-231 KB SK-N-MC
5a
 Inline graphic
 19.70 ± 3.07
 36.85 ± 2.97
 12.60 ± 8.45
5b
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 7.56 ± 2.23
 25.04 ± 10.60
 9.64 ± 2.71
5c
 Inline graphic
 20.03 ± 4.27
 >100
 58.04 ± 21.08
5d
 Inline graphic
 >100
 >100
 >100
5e
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 >100
 >100
 >100
5f
 Inline graphic
 16.47 ± 1.47
 >100
 >100
5g
 Inline graphic
 16.32 ± 2.67
 >100
 >100
5h
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 18.87 ± 0.43
 >100
 >100
5i
 Inline graphic
 7.10 ± 2.99
 >100
 >100
5j
 Inline graphic
 14.23 ± 4.37
 >100
 >100
5k
 Inline graphic
 10.53 ± 0.86
 >100
 >100
Etoposide   21.2 ± 2.12 18.93 ± 1.78 14.04 ± 1.05