Table 1.
The genotypings of A133S in RASSF1A gene on ESCC and GCA patients and normal controls
| Genotypings* |
Control |
ESCC |
GCA |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| n | (%) | n | (%) | P | OR | (95%CI) | n | (%) | P | OR | (95%CI) | |
|
Ala/Ala |
211 |
(89.8) |
99 |
(88.4) |
|
|
|
94 |
(81.0) |
|
|
|
|
Ala/Ser |
23 |
(9.7) |
11 |
(9.8) |
0.96 |
1.02 |
(0.48–2.17) |
18 |
(15.5) |
0.09 |
1.76 |
(0.91–3.41) |
|
Ser/Ser |
1 |
(0.4) |
2 |
(1.8) |
0.24 |
4.26 |
(0.38–47.02) |
4 |
(3.5) |
0.04 |
9.01 |
(0.99–83.31) |
| Ala/Se and Ser/Ser | 24 | (10.2) | 13 | (11.6) | 0.69 | 1.15 | (0.51–2.44) | 22 | (19.0) | 0.02 | 2.06 | (1.09–3.97) |
*: Ala/Ala: homozygous for wild-type codon 133, Ala/Ser: heterozygote for codon 133, Ser/Ser: homozygous for codon A133S.