Table 2.
The profiles of RASSF1A promoter hypermethylation in ESCC and GCA tissues and in normal tissues adjacent to the corresponding ESCC and GCA
| Tissues# | N |
Methylated |
Unmethylated |
P | OR | (95%CI) | ||
|---|---|---|---|---|---|---|---|---|
| n | (%) | n | (%) | |||||
|
ESCC |
143 |
76 |
(53) |
67 |
(47) |
<0.001 |
5.90 |
(2.78–12.52) |
|
ENOR |
62 |
10 |
(16) |
52 |
(84) |
|||
|
GCA |
92 |
60 |
(65) |
32 |
(35) |
<0.001 |
7.50 |
(2.78–20.23) |
| GNOR | 30 | 6 | (20) | 24 | (80) | |||
#: ESCC: esophageal squamous cell carcinoma, ENOR: esophageal normal epithelial tissue, GCA: gastric cardia adenocarcinoma, GNOR: gastric cardia normal epithelial tissue.