Table 5.
MiRNAs differentially expressed in sALS and controls, and predicted recognition elements (MRE) in NFL 3′UTR
| miRNA | Expression in sALS compared to controls | NFL mRNA 3′UTR target | Conservation of MREs |
|---|---|---|---|
| 23a |
down |
S/M/L |
Conserved |
| 23b |
down |
S/M/L |
Conserved |
| 30a |
down |
S/M/L |
Conserved |
| 30b |
down |
S/M/L |
Conserved |
| 146a* |
up |
M/L |
Not conserved |
| 192 |
down |
M/L |
Conserved |
| 193a-5p |
down |
M/L |
Not conserved |
| 215 |
down |
M/L |
Conserved |
| 524-5p |
down |
L |
Not conserved |
| 556-5p |
down |
M/L |
Not conserved |
| 582-3p | down | S/M/L | Not conserved |