Table 1. Probability parameters used in the economic model.

	Base casea	Distribution	References
Vaccine parameters
Vaccine efficacy (%)
Initial vaccine efficacy (14 months)	89.96	Triangular (64;89.96;98)		[29], [30]
Initial vaccine efficacy (12 years)	95.95	Triangular (92;95.95;99)		[29], [30]
Adverse events
Number of AE per 10,000 immunizations	3.48	Beta (4764;13691736)		[48]
Number of AR per 10,000 immunizations	0.02	Beta (27;13696473)		[48]
Vaccination coverage (%)
14 months	95.9	Fixed		[49]
12 years	94.0	Fixed		[50]
Disease parameters
ACWY incidence (per 100,000 persons)	0.15 (age dependent)	Beta (25;16431651)		[15]
Clinical features (%)
Meningococcal disease	65.1	Beta (443;238)		[51], [52]
Meningococcal disease with septic shock	34.9	Dependent of MD		[51], [52]
Case fatality (%)
Case fatality rate MD	2.1	Beta (8;372)		[51]
Case fatality rate MDS	13.0	Beta (21;140)		[51]
Sequelae (%)
Scars	2.8	Beta (16;546)		[4]
Amputations	0.7	Beta (4;558)		[4]
Neurological sequelae	6.9	Beta (127;1707)		[3], [4], [39]
Demographic parameters
Birth cohort	185,000	Fixed		[18]
Adolescent cohort (aged 12 years)	200,000	Fixed		[18]
Probability of being a girl	49.0%	Fixed		[18]
Probability of being a boy	51.0%	Fixed		[18]
Probability of dying of other causes	Age dependent	Fixed		[15], [18]

AE = adverse event, AR = Anaphylactic reactions, MD = meningococcal disease without septic shock, MDS = meningococcal disease with septic shock.

^aValues are presented as percentages or rates.