Table 2. Univariable logistic regression with patient-related factors at the time of malignancy diagnosis as independent variables and oral mucositis as the outcome in all patients (n = 104).

Variables	No oral mucositis	Oral mucositis	Univariable logistic regression
	n = 45	n = 59	OR (95% CI)	P-value
	mean ± SD	mean ± SD
Age (year)	5.9±5.7	7.1±5.3	1.045 (0.971–1.124)	0.238
Gender (M/F)	28/17	38/21	0.910 (0.407–2.035)	0.819
Weight (kg)	25.4±21.8	29.2±20.0	1.009 (0.990–1.029)	0.355
Height (cm)	109.5±39.4	122.0±35.4	1.009 (0.998–1.020)	0.095
BMI (kg/m2)	17.3±3.1	17.4±2.7	1.012 (0.882–1.161)	0.867
BMI-SDS	0.23±1.45	0.25±1.25	1.007 (0.751–1.349)	0.964
Oral variables
DMFT (dmft)	0.6±1.7	0.4±1.1	0.924 (0.699–1.221)	0.578
GBI (≤15%/>15%)	42/3	55/4	1.018 (0.216–4.797)	0.982
Diagnosis				<0.001***
Acute leukemia	6	34	1
Lymphoma	11	3	0.048 (0.010–0.225)	<0.001***
Solid tumors	28	22	0.139 (0.049–0.389)	<0.001***
Other chronic disease (yes/no)	10/35	17/42	1.417 (0.576–3.487)	0.449
Laboratory test
Neutrophils (×109/l)	5.2±4.8	3.6±4.5	0.925 (0.844–1.013)	0.093
Leukocyte (×109/l)	31.6±135.3	43.4±106.6	1.001 (0.997–1.004)	0.621
Lymphocyte (×109/l)	6.1±13.5	7.8±14.6	1.010 (0.978–1.043)	0.558
Thrombocyte (×109/l)	364±306	192±157	0.995 (0.992–0.998)	<0.001***
Hemoglobin (g/l)	112±26	93±30	0.976 (0.960–0.991)	0.002**
Creatinine (µmol/l)	35±16	41±19	1.022 (0.998–1.047)	0.073
HSVa (positive/negative)	10/31	16/41	1.210 (0.483–3.028)	0.684
EBVa (positive/negative)	20/22	30/26	1.269 (0.569–2.829)	0.560
CMVa (positive/negative)	20/22	25/34	0.809 (0.365–1.793)	0.601

BMI, body mass index; BMI-SDS, BMI-standard deviation scores; DMFT (dmft), decayed, missing or filled teeth; GBI, gingival bleeding index; HSV, herpes simplex virus; EBV, Epstein-Barr virus; CMV, cytomegalovirus; SD, standard deviation; OR, odds ratio; CI, confidence interval.

^aBlood antibody reactivity or PCR analysis. Data of HSV in six patients, EBV in six patients, and CMV in three patients were not available.

^** P<0.01,

^*** P<0.001.