Table 2.
Demographic features, ROTEM and CAT results of both groups
| Characteristics | BD patients (N = 23) | Controls (N = 33) | p-value | |
|---|---|---|---|---|
| Age at inclusion (year) |
49 ± 15 |
43 ± 10 |
0.082 |
|
| Female gender (%) |
78 |
63 |
0.241 |
|
| |
INTEM-α (degree) |
77 ± 3 |
74 ± 2 |
<0.010 |
| ROTEM |
INTEM-CFT (sec) |
66 ± 15 |
80 ± 14 |
<0.010 |
| INTEM-MCF (mm) |
61 ± 4 |
57 ± 4 |
<0.010 |
|
| |
Platelet contribution-MCF (%) |
78 (69–79) |
79 (77–81) |
0.090 |
| |
Lag-time (min) |
6.7 ± 1.8 |
5.6 ± 1.1 |
0.025 |
| CAT |
Time-to-peak (min) |
9.6 ± 1.9 |
9.0 ± 1.4 |
0.240 |
| Peak height (nM) |
292 ± 65 |
213 ± 67 |
<0.010 |
|
| ETP (nM × min) |
1543 ± 331 |
1286 ± 292 |
0.010 |
|
| |
Velocity index (nM/min) |
102 (83–127) |
55 (42–90) |
<0.010 |
| |
Platelet count (×103/μl) |
217 (189–287) |
227 (199–247) |
0.785 |
| |
Erythrocyte count (×106/μl) |
4.2 ± 0.4 |
4.3 ± 0.4 |
0.244 |
| |
Fibrinogen (mg/l) |
321 ± 53 |
280 ± 42 |
<0.010 |
| TAT (ng/l) |
19 (17–21) |
15 (12–17) |
<0.010 |
|
| Other parameters |
D-dimer (μg/l) |
293 ± 65 |
270 ± 86 |
0.480 |
| tPA (antigen) (ng/ml) |
17.2 ± 7.2 |
12.4 ± 5.2 |
0.120 |
|
| |
PAI-1 (antigen) (ng/ml) |
19.9 ± 8.6 |
12.6 ± 6.0 |
0.032 |
| |
E-selectin (μg/l) |
24.2 ± 9.3 |
16.8 ± 8.4 |
0.040 |
| C-reactive protein (mg/dl) | 0.2 (0.1-0.5) | 0.1 (0.1-0.4) | 0.046 | |
Results are expressed as the mean ± SD, the median and range (25th-75th percentile) or as absolute value (%).