Table 2.
Controls | Smokers without COPD | Controls vs Smokers without COPD p-value | Smokers with COPD | Controls vs Smokers with COPD p-value | ||
---|---|---|---|---|---|---|
Blood (cells x103/mL) |
Monocytes |
512 |
597 |
ns |
616 |
ns |
363-741 |
482-674 |
516-790 |
||||
Neutrophils |
2914 |
3633 |
0.2 |
4072 |
0.01 |
|
2121-4188 |
2942-3889 |
3456-5392 |
*0.04 |
|||
Lymphocytes |
1828 |
2442 |
ns |
2189 |
ns |
|
1675-2752 |
1857-3148 |
|
1942-2624 |
|||
Eosinophils |
184 |
255 |
ns |
269 |
ns |
|
117-249 |
135-318 |
236-334 |
||||
BAL (cells x106 /L) |
Cells x106/L |
114 |
290 |
0.0001 |
281 |
0.002 |
83.2-129 |
259-523 |
156-351 |
|
|||
Macrophages |
91.3 |
264 |
0.0001 |
242 |
0.001 |
|
79.1-115.7 |
225-498 |
143-305 |
||||
Neutrophils |
3.8 |
12.4 |
0.03 |
8.4 |
0.04 |
|
0.4-5.1 |
3.5-21.5 |
3.6-21.7 |
||||
Lymphocytes |
4.7 |
13.3 |
0.003 |
10.2 |
0.2 |
|
3.6-8.9 |
11.2-23.5 |
3.3-19.8 |
||||
Eosinophils |
0 |
0 |
0.2 |
2.4 |
0.01 |
|
0-0.2 |
0-1.1 |
0.3-4.5 |
||||
Sputum (cells/mg) |
Cells/mg |
715 |
603 |
ns |
652 |
ns |
514-908 |
284-866 |
409-1370 |
||||
Macrophages |
250 |
218 |
ns |
234 |
ns |
|
155-603 |
53.5-444 |
136-424 |
||||
Neutrophils |
396 |
415 |
ns |
501 |
ns |
|
157-490 |
132-591 |
343-786 |
||||
Lymphocytes |
23.2 |
9.3 |
ns |
14.9 |
ns |
|
18.2-31.8 |
7.2-11.3 |
4.5-55.6 |
||||
Eosinophils | 0 |
1.3 |
ns | 8.2 |
ns | |
0-5.0 | 0-2.6 | 0.6-16.8 |
Data are presented as median and 25th – 75th percentile. Comparisons between groups were made using Kruskal-Wallis test followed by Mann–Whitney test when appropriate. * indicate p-value for comparison between smokers with and without COPD.