Figure 2. ER stress protein markers are not induced in TLR4^−/− mice after a high-fat diet.

(A) Protein expression of BiP and phosphorylated eIF2α in skeletal muscle, liver and subcutaneous adipose tissue of wild-type (WT) and TLR4 knockout (TLR4^−/−) mice fed with a standard (chow) or a high-fat diet (HFD). Results are presented as means ± SEM (n = 8–10), * P<0.05, ** P<0.01, *** P<0.001. (B) Illustration of the data presented in panel A.