Figure 3. ER stress mRNA markers are not up-regulated in TLR4^−/− mice after a high-fat diet.

mRNA level of XBP1u (X-box-binding protein 1 unspliced), XBP1s (X-box-binding protein 1 spliced) and CHOP (C/EBP homologous) in skeletal muscle, liver and subcutaneous adipose tissue of wild-type (WT) and TLR4 knockout (TLR4^−/−) mice fed with a standard (chow) or a high-fat diet (HFD). Results are expressed as means ± SEM (n = 8–10), * P<0.05, ** P<0.01, *** P<0.001.