Table 6.RFC1 80G > A genotype prevalence and allele frequencies in subjects with low and high tHcy and normal and NTD subjects.
| |
Leucocytes |
|
Placenta |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| |
Low tHcy |
|
High tHcy |
|
Normal |
|
NTD |
|||||
| RFC1 80G > A | n | % | n | % | n | % | n | % | ||||
| |
|
|
|
|
|
|
|
|
|
|
|
|
| GG |
6 |
(27) |
|
8 |
(33) |
|
8 |
(21) |
|
22 |
(32) |
|
| GA |
12 |
(54) |
|
12 |
(50) |
|
23 |
(61) |
|
33 |
(49) |
|
| AA |
4 |
(18) |
|
4 |
(17) |
|
7 |
(18) |
|
13 |
(19) |
|
|
Total |
22 |
|
|
24 |
|
|
38 |
|
|
68 |
|
|
| |
|
|
|
|
|
|
|
|
|
|
|
|
| |
χ2 = 0.22 |
|
χ2 = 0.02 |
|
χ2 = 1.7 |
|
χ2 = 0.01 |
|||||
| |
|
|
|
|
|
|
|
|
|
|
|
|
| p(G) |
0.583 |
|
|
0.545 |
|
|
0.513 |
|
0.566 |
|||
| q(A) | 0.417 | 0.454 | 0.487 | 0.434 | ||||||||