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. 2013 May 31;8(5):e65719. doi: 10.1371/journal.pone.0065719

Figure 1. Representative chromatograms.

Figure 1

(A) pure standard of 5 ng/ml N-desmethyl-olanzapine, 5 ng/ml olanzapine and 80 ng/ml clozapine dissolved in mobile phase without extraction; (B) pure standard of 20 ng/ml N-desmethyl-olanzapine, 20 ng/ml olanzapine and 80 ng/ml clozapine dissolved in mobile phase without extraction; (C) blank extracted plasma sample; (D) Extracted plasma sample spiked with 5 ng/ml N-desmethyl-olanzapine, 5 ng/ml olanzapine and 80 ng/ml clozapine; (E) Extracted plasma sample spiked with 20 ng/ml N-desmethyl-olanzapine, 20 ng/ml olanzapine and 80 ng/ml clozapine.